Clomid Clomiphene: Purpose, Dosage, Side Effects, Risks

Clomid Clomiphene: Purpose, Dosage, Side Effects, Risks

Other drugs may interact with clomiphene, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. When it works, Clomid is one of the most affordable fertility treatments on the market. Depending on your infertility diagnosis, height, and weight – you’ll take anywhere from five to 15 Clomid tablets per cycle. Each pill costs about $5 – although many pharmacies offer “discounts” for bulk purchases. If ovulation appears not to have occurred after the first course of therapy, a second course of 100 mg daily (two 50 mg tablets given as a single daily dose) for 5 days should be given.

  • Additionally, if an individual ovulates for three cycles but also does not get pregnant, experts recommend stopping Clomid and trying another option.
  • Clomid is often prescribed by primary care physicians or OB-GYNs before they refer a couple to see a fertility specialist for more specialized care.
  • Do not take a double dose to make up for a forgotten tablet.
  • One risk of taking Clomid is the increased chance of developing ovarian hyperstimulation syndrome (OHSS).
  • Clomid has been successfully used to treat infertility for more than 50 years, which makes it one of the safest and long-lived fertility treatment medications on the market.

However, if the patient fails to ovulate, a second course of 100 mg/day for 5 days may be given as early as 30 days following the initial course. A third course of 100 mg/day for 5 days may be given after 30 days, if necessary. Treatments beyond three cycles of Clomid, dosages greater than 100 mg once a day, and/or course durations beyond 5 days are not recommended by the manufacturer.

Clomiphene (Oral Route)®, also known as clomiphene citrate, is a medication designed to improve a woman’s chance of pregnancy by inducing ovulation and stimulating follicle growth in the ovaries. AtFertility Center of San Antonio, we may recommend this fertility medication as a safe and effective approach to treating couples with unexplained infertility. It is also beneficial for women who have an irregular menstrual cycle or do not ovulate on their own due to PCOS (polycystic ovarian syndrome). To find out if you are a good candidate, we invite you to visit our San Antonio, TX, clinic for a fertility evaluation.

  • Ovulation occurs most often 6 to 7 days after a course of clomifene.
  • These cysts are rarely harmful and will usually disappear on their own.
  • Dosage varies from patient to patient, depending on your infertility diagnosis as well as your response to the treatment, which will be closely monitored by your doctor.

Long-term use of clomiphene may increase the risk of ovarian cancer. Clomiphene should not be used for more than about six cycles. Talk to your doctor about the risks of taking this medication.

Clomid and artificial insemination, IUI

If ovulation occurs but you do not get pregnant after 3 treatment cycles, your doctor may stop treatment and evaluate your infertility further. While OB/GYNs do have the ability to diagnose infertility and prescribe Clomid, the best fertility success rates and pregnancy outcomes occur for women who seek treatment from a fertility specialist. This will also assure you start out with the first, best treatment for your diagnosis (what if it were your partner who is actually infertile?). About 60 to 85% of people who take Clomid can ovulate normally again. Overall, you have about a 4 to 12% chance of getting pregnant each menstrual cycle while on Clomid. Most women do well on Clomid, but treatment with Clomid can be emotionally intense.

  • You must remain under the care of a doctor while you are using clomiphene.
  • If this happens, stop the drug immediately and contact either myself or Accident & Emergency of your nearest hospital.
  • Increased dosages of Clomid may actually worsen the side effects.
  • One of the reasons doctors and their patients prefer Clomid is that it has reasonable success rates and minimal (low-risk) side effects.

This activity discusses the applications of clomiphene citrate in addressing infertility challenges, with a particular focus on patients diagnosed with polycystic ovarian syndrome (PCOS). Many research studies and meta-analyses have found that hormonal infertility treatments do not increase the risk of breast cancer. Similarly, there does not seem to be much evidence that these drugs raise the risk of ovarian cancer. Officially known as clomiphene citrate (also Serophene), the FDA approved Clomid for use as an oral, non-steroidal fertility treatment in 1967.

When to take Clomid

Because Clomid can be prescribed by a gynecologist and doesn’t require a fertility specialist, it’s usually the very first fertility treatment tried for most couples. The most common starting dose is one tablet a day for five days, beginning on the third, fourth or fifth day of your menstrual cycle. Depending on the brand and dosage of medication prescribed, Clomid typically costs somewhere between $10 and $100 per cycle. When beginning treatment, we can prescribe tablets containing 50mg to take daily, between day three through seven of the menstrual cycle. In other cases, we may recommend that you take Clomid on day five through nine of your menstrual cycle.

More about clomiphene

I specialise in low and high risk pregnancies, general gynaecology, infertility and laparoscopic (keyhole) surgery. One important side effect is the possibilityof multiple births. The probability of having twins while taking this medication is 7% (meaning 7 out of 100 women taking Clomid will get pregnant with twins). One reason for that is the possible increased risk of developing ovarian cancer. Your doctor will give you specific directions on how to use this medication.

Who Should Take Clomid?

Women with unexplained infertility, or no obvious reason for their inability to conceive, should only take Clomid under the supervision of an OB/GYN for one to three cycles. After that, they should consult with a fertility specialist to begin infertility testing and accurate diagnosis. This is one of the reasons fertility specialists are fans of Clomid. Multiples pregnancies are considered high risk pregnancies, and that’s the last thing you want after all your hard work to get pregnant. Even though you take Clomid for only five days, the chain reaction that starts with your first pill continues throughout the month. You should ideally take the Clomid at the same time every day, and some say that taking the pill before bed can help you sleep through some of the side effects.

Ovulation-Inducing Fertility Drugs

Side effects do not appear to be dose-related, as patients may experience these common side effects even on the lowest dose of the medication. Most people have either no side effects or mild symptoms only. Your doctor will likely instruct you to take Clomid at the beginning of your menstrual cycle, typically between days 3 and 5. Then, you’ll live your life as normal until your next cycle is about to begin. If you’re still not pregnant, your doctor may recommend another course of Clomid. Generally, your doctor won’t recommend more than six courses of Clomid, as if it hasn’t worked by then, there is likely another fertility issue at play.


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